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目的了解阑尾炎手术患者围手术期抗菌药物的应用情况。方法回顾性调查我院2007年1月至2008年12月258例阑尾炎手术患者围手术期抗菌药物的应用情况。结果阑尾炎手术患者抗菌药物应用率达100%,其中预防性用药占82.6%。抗菌药物应用率列前5位的分别为甲硝唑(占26.1%)、替硝唑(占14.7%)、美洛西林钠(占6.0%)、头孢呋辛(占5.5%)和头孢替安(占5.3%)。联合用药中二联比例最大。结论我院阑尾炎手术患者围手术期应用抗菌药物仍存在预防性用药时间偏长、部分应用抗菌药物起点偏高、联用方式不恰当等,应加强监管,以提高合理用药水平。
Objective To understand the application of perioperative antibiotics in patients with appendicitis. Methods A retrospective investigation of our hospital from January 2007 to December 2008 258 cases of perioperative patients with appendicitis in the application of antimicrobial agents. Results The application rate of antibacterials in patients with appendicitis was 100%, of which 82.6% were prophylactic medication. The top 5 antibacterials were metronidazole (26.1%), tinidazole (14.7%), mezlocillin (6.0%), cefuroxime (5.5%) and cefotiam Ann (5.3%). Combined medication in the largest proportion of two. Conclusion There are still some preventive drugs for perioperative application of antimicrobial agents in patients with appendicitis in our hospital. Prophylactic medication is still used for a long time. Some of them use high starting point of antimicrobial drugs and improper combination method. Therefore, the supervision should be strengthened so as to raise the reasonable level of medication.