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目的观察奥曲肽治疗肠梗阻的疗效。方法将76例肠梗阻患者随机分为观察组和对照组各38例。对照组给予常规治疗,包括禁食、胃肠减压、纠正水电解质和酸碱平衡紊乱、全胃肠外营养以及应用抗生素;观察组在常规治疗基础上加用奥曲肽(善宁)0.1 mg皮下注射每8 h1次。观察和比较两组治疗前后临床症状及体征改善情况、胃肠减压量等。结果观察组临床症状明显改善,胃肠减压量明显减少,住院时间明显缩短,与对照组相比差异具有统计学意义。结论在常规治疗基础上,加用奥曲肽治疗各种类型肠梗阻,可明显改善临床症状,缩短住院时间,提高保守治疗的成功率。
Objective To observe the curative effect of octreotide on intestinal obstruction. Methods 76 patients with intestinal obstruction were randomly divided into observation group and control group, 38 cases each. The control group were given routine treatment, including fasting, decompression of the gastrointestinal tract, correction of water and electrolyte and acid-base balance disorders, total parenteral nutrition and the use of antibiotics. The observation group was given octreotide 0.1 mg subcutaneously on the basis of routine treatment Injection every 8 h1 times. Observe and compare the clinical symptoms and signs of two groups before and after treatment to improve the situation, such as gastrointestinal decompression. Results The clinical symptoms of the observation group were significantly improved, the gastrointestinal decompression volume was significantly reduced, hospitalization time was significantly shorter, compared with the control group, the difference was statistically significant. Conclusion On the basis of routine treatment, plus octreotide treatment of various types of intestinal obstruction, can significantly improve clinical symptoms, reduce hospital stay and improve the success rate of conservative treatment.