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目的 分析评价移动应用程序(APP)对流动儿童预防接种健康教育干预的效果.方法 按分层随机方法选择流动儿童的女性监护人169人和172人分别作为实验组和对照组,分别以移动APP、传统方式进行健康教育干预,比较两组监护人的预防知识得分和儿童14剂次国家免疫规划(NIP)疫苗接种率.结果 实验组和对照组干预后预防接种知识得分分别比干预前提高24.50±6.78分和10.87±4.82(t=-21.41,P＜0.05).实验组儿童乙型肝炎疫苗第三剂次(HepB3)、乙型脑炎减毒活疫苗(JE-L)、A群脑膜炎球菌多糖疫苗第二剂次(MPV-A2)和麻疹风疹联合减毒活疫苗(MR)的接种率高于对照组x2=4.06,P＜0.05;x2=6.46,P＜0.05;X2 =5.87,P＜0.05;x2=6.63,P＜0.05).结论 移动APP健康教育干预可有效提高流动儿童监护人预防接种知识知晓程度和部分NIP疫苗的接种率.“,”Objective To analyze and evaluate the effect of a mobile phone application (APP) on health education for migrant children and vaccination coverage.Methods A stratified random sampling method was used to select 169 and 172 female guardians of migrant children as the experimental and the control groups,respectively.The health education intervention was a mobile APP for the experimental group,while the control group received traditional standard educational practices.We compared the two groups on guardians' immunization knowledge and coverage rates of 14 doses of vaccines in the National Immunization Program (NIP).Results Guardians' scores on immunization knowledge after the intervention increased by 24.50-±6.78 points and 10.87 ±4.82 points (t =-21.41,P ＜0.05) in the experimental group and the control group,respectively,compared with before the intervention.Coverage rates of the third dose hepatitis B vaccine (HepB3),Japanese encephalitis attenuated live vaccine (JE-L),the second dose of group A meningococcal polysaccharide vaccine (MPV-A2),and measles and rubella attenuated live vaccine (MR) among children in the experimental group were higher than in the control group (x2 =4.06 P ＜ 0.05;x2 =6.46 P ＜ 0.05;x2=5.87,P ＜ 0.05;x2 =6.63,P ＜ 0.05) Conclusions Health education with a mobile phone APP can improve guardians' immunization knowledge and increase coverage of NIP vaccines among migrant children.