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目的 探讨轮状病毒(RV)肾损害的发生概况及预后。方法 对38 例入院时均解黄色水样便,大便培养阴性,轮状病毒检测阳性的患儿进行治疗前后尿常规,血、尿β2 -微球蛋白(β2 -MG)和血尿素氮及肌酐的检查。结果 38例患儿中共11例出现尿常规异常,占28%,血清β2-MG升高者8例(21%),尿中β2-MG升高者6例(16%),两者同时升高者2例(5%)。血尿素氮及肌酐检查正常。抗链球菌溶血素O均为阴性。该11 例尿常规出现异常的患儿,RV肠炎治愈后复查尿常规、血和尿β2-MG均恢复正常。结论 RV可以造成的肾脏损害,临床上短期预后良好。
Objective To investigate the occurrence and prognosis of rotavirus (RV) nephropathy. Methods Thirty - eight children were admitted to hospital with yellow watery stool samples, urine stool, urine and urine urea nitrogen, and creatinine (BUN) before and after treatment in children with stool culture negative and rotavirus positive. Checked. Results Of the 38 children, 11 cases had abnormal urine, accounting for 28%, 8 cases (21%) with elevated serum β2-MG and 6 cases (16%) with elevated β2-MG in urine. The high in 2 cases (5%). Blood urea nitrogen and creatinine were normal. Anti-streptolysin O were negative. The 11 cases of urinary routine abnormalities in children, RV enteritis recurred urine routine review, blood and urine β2-MG were returned to normal. Conclusion RV can cause kidney damage, clinical short-term prognosis is good.