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应用改进的亲和组化法检测５９例胃癌雌激素受体状况，流式细胞仪检测其中５６例ＤＮＡ含量。结果显示：５９例胃癌ＥＲ检测阳性１９例（３２．２％）ＥＲ阳性者多见于≥５０岁者和ＢｏｒｒｍａｎｎⅢ、Ⅳ型者。ＥＲ阳性者ＤＩ值较低，以二倍体较多见，而ＥＲ阳性异倍体胃癌淋巴结转移和浆膜浸润多见。结果表明：胃癌组织中存在雌激素受体，联合检测ＥＲ和ＤＮＡ可为胃癌内分泌治疗和预后评估提供更多的生物学依据。
Fifty-nine cases of gastric cancer with estrogen receptor were detected by modified affinity histochemistry method. 56 DNA samples were detected by flow cytometry. The results showed that 59 cases of gastric cancer ER positive in 19 cases (32.2%) were more common in ER-positive patients and Borrmann III, IV type. The DI value of ER-positive patients was lower, which was more common in diploids, while lymph node metastasis and plasma membrane infiltration were more common in ER-positive aneuploid gastric cancer. The results showed that the existence of estrogen receptors in gastric cancer tissues combined detection of ER and DNA can provide more biological basis for endocrine therapy and prognosis assessment of gastric cancer.