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目的:探讨糖尿病采用胰岛素治疗的临床效果。方法:本次选取100例糖尿病患者,均为2013年1月至2014年1月收治,随机分组,在应用阿卡波糖药物基础上,分别采用甘精胰岛素(观察组50例)与中效低糖蛋白锌人胰岛素(对照组50例)效果进行比较。结果:观察组低血糖率为6%,明显低于对照组22%(P<0.05)。相较治疗前无差异的糖化血红蛋白(HbAlc)、餐后2 h血糖(2 h PG)、空腹血糖(FBG)指标,治疗后两组观察指标均有下降,HbAlc、FBG组间差异不明显,但2 h PG观察组下降幅度优于对照组(P<0.05)。结论:糖尿病采用甘精胰岛素治疗,具理想的降血糖效果,且可防范低血糖事件发生,有较高临床应用价值。
Objective: To investigate the clinical effect of insulin therapy on diabetes mellitus. Methods: A total of 100 patients with diabetes mellitus were selected from January 2013 to January 2014 and randomly divided into groups. On the basis of acarbose drug, insulin glargine (observation group, 50 cases) and mid-dose Low-glycoprotein zinc human insulin (control group, 50 cases) were compared. Results: The hypoglycemia rate in the observation group was 6%, which was significantly lower than that in the control group (P <0.05). HbAlc, 2 h postprandial blood glucose (2 h PG) and fasting blood glucose (FBG) were significantly lower than those before treatment, but no significant difference between HbAlc and FBG groups However, the decrease in 2 h PG group was better than that in control group (P <0.05). Conclusion: Diabetes using insulin glargine treatment, with an ideal hypoglycemic effect, and can prevent hypoglycemic events, have a high clinical value.