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库兴氏综合征的产生是由于肾上腺肿瘤,或继发于垂体的,或由异位分泌的 ACTH 不正常刺激引起双侧肾上腺皮质增生所致。在这种皮质醇高分泌状态下的中度至重度高血压,首先由 HarveyCushing 报告。据统计,有约70%的患者有高血压,并且常是最初就诊的原因。作者观察了148例患者,垂体依赖性库兴氏征者,64%患有高血压。
Cushing’s syndrome is caused by adrenal hyperplasia due to adrenal tumors, secondary to the pituitary gland, or abnormal stimulation of ectopically secreted ACTH. Moderate-to-severe hypertension in this state of hypercortisol secretion is first reported by HarveyCushing. According to statistics, about 70% of patients have high blood pressure and are often the reason for initial visits. The authors observed 148 patients with pituitary-dependent Cushing’s syndrome and 64% had hypertension.