Galen把脾脏称作是一个“充满着神秘色彩的器官”。19世纪末及20世纪初Thomas Brycmt(1864)、Spencer Wells(1887)、Micheli(1910)、Eppinger(1913)和Kaynelson(1916)等通过临床上的探索,开辟了对某些血液病行脾切除治疗这一途径。20世纪中叶以来,组织学、生理学及病理生理学方面的研究使人们对脾脏的结构、功能,脾脏与其他脏器的关系及其在疾病过程中的作用有了更加深入的了解。 Galen calls the spleen a “mysterious organ.” Through the clinical exploration, Thomas Brycmt (1864), Spencer Wells (1887), Micheli (1910), Eppinger (1913) and Kaynelson (1916) in the late 19th century and early 20th century opened the door to spleen resection for some hematological diseases This approach. Since the mid-20th century, the study of histology, physiology and pathophysiology has led to a more in-depth understanding of the structure and function of the spleen, the relationship between the spleen and other organs and its role in the disease process.