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目的:探讨超高度近视眼视网膜神经纤维层厚度(RNFLT)光学相干断层成像(OCT)各个象限变化规律,为使用OCT检测超高度近视人群RNFLT诊断和鉴别诊断提供依据。方法选取正常对照组35例(55眼),超高度近视组57例(92眼),按等效球镜度分为三组:第I组:-10:00~-12.00D组,31例(57眼);第II组:-12.00~-15.00D组,15例(21眼);第III组:-15.00D组,11例(14眼)。采用OCT检测RNFLT,比较超高度近视患者RNFLT变化规律,并比较与正常对照组RNFLT的差别,研究超高度近视患者RNFLT与屈光度的相关性。结果超高度近视眼组与正常对照组相比除了颞侧RENFL平均厚度变薄。两组间对应的参数差异有统计学意义(<0.05)。超高度近视患者中在不同屈光度组RNFLT比较差异有统计学意义(<0.05),除了颞侧,屈光度的绝对值与RNFLT成负相关(r<0,<0.05),鼻下相关性最高,颞上相关性较低。结论在超高度近视患者中,除了颞侧,OCT检测各个象限的RNFLT变薄。屈光度的绝对值与RNFLT成负相关。因此,在评价RNFLT改变时要重视超高度近视RNFLT的规律性特征。“,”Objective To study the feature of super-high myopia retinal nerve fiber layer thickness (RNFLT) and to provide the diagnosis basis by optical coherence tomography (OCT). Methods 35 cases (55 eyes) normal control and 57 cases (92 eyes) super-high myopia were tested by OCT. They were divided into three groups according the e-quivalent spherical mirrors degrees: the group I: - 10:00~-12.00D group, 31 cases (57 eyes); Group II: -12.00~-15.00D group, 15 cases (21 eyes);Group III: <-15.00 group D, 11 cases (14 eyes). Using OCT test RNFLT, compare the change rule of RNFLT in super -high myopia patients. Results Super-high myopia group compared with normal control group except for average thickness of RENFL was thinning in temporal quadrant. The parameters of the corre-sponding difference between the two groups was statistically significant ( <0.05). The RNFLT comparative difference in super-high myopia patients in different group was statistically significant ( <0.05). Except the temporal side, the absolute value and RNFLT negative correlation ( < 0, <0.05), the highest correlation under the nose, the temporal correlation is low. Conclusion In super high myopia patients, in addition to the temporal side, each quadrant of RNFLT OCT thins. The absolute value of diopter and RNFLT are in negative correlation. Therefore, it ought to attach great im-portance to the regularity of super high myopia RNFLT characteristics when evaluating RNFLT change.