论文部分内容阅读
目前流行性感冒(流感)疫苗产能尚不能满足发生流感大流行时的需求,而且由于免疫原性受被接种者的年龄、接种部位、接种途径以及身体免疫机能的不同而有所差异。因此在维持免疫原性的前提下,采用低剂量接种十分重要。研究发现,一些疫苗采用皮内接种,而不是传统的肌内或皮下接种,可以减少接种剂量,而同时又保持免疫原性。
At present, the vaccine production of influenza (influenza) is not enough to meet the demand of influenza pandemic. However, the immunogenicity varies depending on the age, site of vaccination, route of immunization and immune function of the immunized person. Therefore, to maintain the immunogenicity of the premise, the use of low-dose vaccination is very important. The study found that vaccination with some vaccines, rather than the traditional intramuscular or subcutaneous inoculation, can reduce the dose of vaccination while remaining immunogenic.