患女,4岁,因经常上呼吸道感染肌注入血丙种球蛋白(下称丙球)3毫升。注射后5分钟,患儿突然面部水肿、潮红、声音嘶哑,未用过其他药物,无药物过敏史。肌注的丙球在有效期内,药品未发生沉淀、混浊。体检:体温37.3℃,神萎,呼吸稍促,面部水肿、潮红,伴密集针尖样出血性皮疹,压之不褪色。躯干、四肢无皮疹。心率120次/分,肺无殊,血压12/7kPa。查白细胞8.2×10~9/L,中性粒细胞52％,淋巴细胞48％,血小板140×10~9/L,考虑丙球过敏,立即吸O_2,静注地塞 Affected women, 4 years old, due to frequent upper respiratory tract infection muscle gamma globulin (hereinafter referred to as c ball) 3 ml. Five minutes after injection, the child suddenly had facial edema, flushing, hoarseness, no other medication, no history of drug allergy. Intramuscular injection of c-ball in the period of validity, the drug did not precipitate, cloudy. Physical examination: body temperature 37.3 ℃, Shen Wei, breathing a little urgency, facial edema, flushing, with dense needle-like hemorrhagic rash, the pressure of fade. Torso, no rash on all limbs. Heart rate 120 beats / min, no lungs, blood pressure 12 / 7kPa. Check the white blood cells 8.2 × 10 ~ 9 / L, 52% of neutrophils, lymphocytes 48%, platelets 140 × 10 ~ 9 / L, consider C ball allergy, immediately inhaled O_2, intravenous injection