DNA免疫是近年发展起来的一种新型抗体制备法。DNA免疫克服了传统蛋白质免疫方法的缺陷,能更为有效地激发机体的体液和细胞免疫应答。尤其是在仅知DNA编码而不能获得目的蛋白或获得的抗原蛋白为低免疫性的情况下,蛋白质免疫将很难得到特异性的抗体,但通过DNA免疫可制备高效价特异性的抗体,这为某些疾病如病毒性疾病和肿瘤等的诊断和免疫治疗开拓了新的途径。 DNA immunization is a new antibody preparation method developed in recent years. DNA immunization overcomes the shortcomings of the traditional methods of protein immunization and can more effectively stimulate the body’s humoral and cellular immune responses. In particular, when only the DNA encoding is known and the target protein can not be obtained or the obtained antigenic protein is hypoallergenic, it is difficult to obtain specific antibodies by protein immunization, but high titer-specific antibodies can be prepared by DNA immunization, which For some diseases such as viral diseases and cancer diagnosis and immunotherapy has opened up new avenues.