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目的:分析急性白血病患者骨髓涂片中异常嗜酸粒细胞,探讨其在分型诊断中的意义。方法:通过光镜观察急性白血病骨髓涂片中嗜酸粒细胞的数量及形态。结果:242例急性白血病骨髓涂片中嗜酸粒细胞均有不同程度的成熟障碍及核左移,M4EO、M2a及M2b显著异常改变,而M3和ALL的嗜酸粒细胞仅有少数患者轻度改变。结论:M4EO嗜酸粒细胞无论是成熟还是幼稚均大于5%,并伴有形态异常,是急性白血病分型诊断重要参考指标之一。
Objective: To analyze the abnormal eosinophils in the bone marrow smears of patients with acute leukemia and to explore its significance in the classification diagnosis. Methods: The number and morphology of eosinophils in acute leukemia bone marrow smears were observed by light microscopy. RESULTS: Eosinophils in 242 leukemia bone marrow smears all had different degrees of maturation disorders and leftward shifts, and M4 EO, M2a, and M2b were significantly altered. However, only a few patients with M3 and ALL had eosinophilia. change. Conclusion: M4EO eosinophils, whether mature or immature, are more than 5%, with morphological abnormalities. It is one of the important reference indexes for the diagnosis of acute leukemic type.