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在冈比亚的一个村庄,埃及血吸虫感染的强度和发病高峰见于20岁的人群,随后下降。10岁以下儿童经吡喹酮治疗后再感染不仅常见而且严重,但15岁以上者极少。说明抗埃及血吸虫感染的保护性免疫是逐渐产生的。感染强度和发病因年龄增长而下降的免疫学机制以15岁以上最为完善。血清抗体水平检测发现,年龄与抗血吸虫IgE和IgG_4抗体水平有关。IgE水平以15岁以上年龄组最高,可以认为此抗体与抗感染有关。
In a village in the Gambia, the intensity and incidence of schistosomiasis infection in Egypt was seen in the 20-year-old population, before declining. Praziquantel treatment of children under the age of 10 and then not only common and severe re-infection, but very few 15 years of age or more. That the protective immunity against schistosomiasis japonica is gradually generated. The immunological mechanisms that reduce the intensity and incidence of infection as they age are the most complete over the age of 15. Serum antibody levels detected, age and anti-schistosome IgE and IgG4 antibody levels. IgE levels in the age group over the age of 15 the highest, can be considered that this antibody and anti-infection.