AIM- To evaluate the role of pentavalent: Tc-99m dimercaptosuccinic acid [Tc-99m (V) DMSA] in the diagnosis of ischemic colitis.METHODS: Fourteen patients with endoscopically and histologically confirmed ischemic colitis were included in the study.Tc-99m (V) DHSA scintigraphy was performed within 2 d after colonoscopy.Images were considered positive when an area of increased activity was observed in the region of interest and negative when no abnormal tracer uptake was detected.RESULTS: In 3 out of the 14 patients,Tc-99m (V) DMSA images showed moderate activity in the bowel.The scintigraphic results corresponded with the endoscopic findings.In the other 11 patients,no abnormal tracer uptake was detected in the abdomen.CONCLUSION: Besides the limited number of patients,Tc-99m (V) DMSA could not be considered as a useful imaging modality for the evaluation of ischemic colitis.