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目的了解外科手术部位白色念珠菌感染状况及其与抗生素应用的关系,采取预防和控制措施。方法采用回顾性调查方法,对60例外科手术切口部位出现的白色念珠菌感染病例进行了调查。结果在2004年4月~2007年5月期间,该医院外科发生60例外科手术切口部位白色念珠菌感染病例。这些感染患者都在术后采取头孢类+喹诺酮类抗生素联合用药,疗程为9~12 d。头孢类抗菌药物使用构成比依次为头孢呋辛钠38.33%,头孢哌酮钠33.33%,头孢唑肟钠28.33%,氧氟沙星80%,克林霉素20%。结论外科手术切口部位白色念珠菌感染与抗生素使用有一定关系,提示应加强抗菌药物用药管理。
Objective To understand the status of Candida albicans infection in surgical site and its relationship with the application of antibiotics and to take preventive and control measures. Methods A retrospective survey was conducted to investigate the incidence of Candida albicans in 60 surgical incision sites. Results From April 2004 to May 2007, 60 cases of C. albicans infection at the surgical incision site occurred in the hospital. These patients were infected with cephalosporins + quinolone antibiotics combined treatment, treatment for 9 ~ 12 d. The composition ratio of cephalosporin antibacterials was 38.33% of cefuroxime sodium, 33.33% of cefoperazone sodium, 28.33% of ceftizoxime sodium, 80% of ofloxacin and 20% of clindamycin. Conclusion Surgical incision site Candida albicans infection and antibiotics have a certain relationship, suggesting that drug administration should be strengthened antimicrobial agents.