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登革热是一种流行于热带、亚热带的虫媒传染病,是广东省的主要传染病之一。本文根据广东省1978～1999年历年急性传染病疫情报表资料,以本地户口登革热病例作统计对象,用年平均人口进行统计,计算出广东省历年登革热的发病率和死亡率,报道了广东省1978～1999年登革热发病动态,共发生7次流行,涉及年份18年,有4年间歇期。每年病例数在1～452674例之间,发病率在0.002～789.94/十万之间,死亡率波动在0～0.470/十万之间;出现两次大流行,第一次是1980年,发病率为789.94/十万,第二次是1986年,发病率为188.71/十万;患者主要为典型的登革热,较少出现登革出血热和登革休克综合征,死亡率和病死率较低,波动在0～0.470/十万、0～0.81%之间;发病地区集中在南部、中部地区,其中海南行政区(即今之海南省)最高,1978～1987年合计病例达596900例,其次是湛江地区、佛山地区和广州市,1978～1999年合计病例分别为29384例、26439例和11788例;时间分布全年各月均有发生,发病高峰期在7～10月份,占全年发病例数的73.66%,发病低谷在12～3月份,仅占全年发病例数的2.43%;由D1～D4型病毒反复、交替引起流行,大多数年份由单一病毒型引起,仅在1991年和1993年出现两型病毒混合感染。
Dengue is a zoonotic disease endemic to the tropics and subtropics and one of the major infectious diseases in Guangdong Province. According to the data of epidemic situation of acute infectious diseases from 1978 to 1999 in Guangdong Province, taking the local population of dengue fever as the statistical object, the annual average population was used to calculate the incidence and mortality of dengue fever in Guangdong Province in the past years. ~ The incidence of dengue fever in 1999, a total of 7 epidemic, involving the year 18 years, 4-year interval. The number of cases per year ranged from 1 to 452,674 cases, with a morbidity of 0.002 to 789.94 per 100,000 and a mortality rate of 0 to 0.470 per 100,000; two pandemic occurrences, the first occurring in 1980 The rate was 789.94 per 100,000 and the second was in 1986 with an incidence rate of 188.71 per 100,000. The patients were mainly dengue fever with less dengue haemorrhagic fever and dengue shock syndrome with lower mortality and mortality , Fluctuating between 0-0.470 per 100,000 and 0-0.81%. The incidence areas are concentrated in the southern and central regions, with the highest in Hainan Province (now Hainan Province), with a total of 596,600 cases in 1978-1987, followed by Zhanjiang The total number of cases from 1978 to 1999 were 29,384 cases, 26439 cases and 11,788 cases, respectively. The time distribution occurred in all months of the year and peaked from July to October, accounting for the annual number of cases Of the total incidence was 73.66% of the total, while the lowest incidence was in December and March, accounting for only 2.43% of the total number of cases in the whole year. The virus was repeatedly caused by D1 ~ D4 viruses and caused the epidemic alternately. Most of the years were caused by a single virus type only in 1991 and 1993 There are two types of virus mixed infection.