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卡维地洛(Carvedilol)是一具有β肾上腺素受体阻滞的多种附加作用的神经激素拮抗剂,非选择性的阻滞β受体并兼有基于αl受体阻滞的血管扩张作用,是第三代β受体阻滞剂,高浓度有阻滞钙通道和抗氧化作用。因具有β受体阻滞作用,可抑制交感神经兴奋和儿茶酚胺分泌,从而减慢心率、降低血压、减弱心肌收缩力、降低心肌耗氧量;因具有αl受体阻滞作用,可以降低周围血管和容量血管的阻力,从而协助降压;因αl受体的高度选择性,故能保留对去甲肾上腺素的释放,防止心动过速,而没有不良代谢作用,对血脂有良好影响。药
Carvedilol is a multi-additive neuroleptic antagonist with beta adrenoceptor blockade, which selectively blocks beta receptors and combines both alpha 1 receptor blockade-based vasodilator effects , Is the third generation of beta blockers, high concentrations of calcium channel block and anti-oxidation. Because of the role of β blockers, can inhibit sympathetic excitement and catecholamine secretion, thereby slowing heart rate, lower blood pressure, reduce myocardial contractility and reduce myocardial oxygen consumption; with α1 receptor blockade can reduce the surrounding blood vessels And capacity of the vascular resistance to help depressurization; α1 receptor highly selective, it can retain the release of norepinephrine, to prevent tachycardia, without adverse metabolic effects, have a good effect on blood lipids. medicine