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神经类固醇是指在脑内合成的中枢源性类固醇和经血脑屏障进入中枢神经系统发挥作用的外周类固醇及它们的代谢衍生物。按神经类固醇与ＧＡＢＡ受体的作用方式 ,可将其分为γ 氨基丁酸 (ＧＡＢＡ)受体激动性和ＧＡＢＡ受体拮抗性神经类固醇 ,前者主要包括 3α 5α 四氢孕酮 (3α
Nervous steroids refer to centrally-derived steroids synthesized in the brain and peripheral steroids that enter the central nervous system via the blood-brain barrier and their metabolic derivatives. According to the mode of action of neurosteroids and GABA receptors, they can be divided into gamma aminobutyric acid (GABA) receptor agonist and GABA receptor antagonist neurosteroid. The former mainly includes 3α5α tetrahydroprotetone (3α