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目的:调查分析复方制荆诱发的不良反应。方法:对本院1994年1月~1998年12月由复方制剂诱发的不良反应病例的类型、临床表现以及诱发药物等进行分析。结果:复方制剂诱发的不良反应75例,占全部285倒不良反应病例的26.3%,中、重度症状者占36%,涉及12个器官/系统类型,诱发药品35个品种,有既往药物不良反应史者占21.3%。结论:临床应高度重视时复方制剂的不良反应监测与相关性研究.提高复方制剂的用药安全性。
Objective: To investigate and analyze the adverse reactions induced by compound Jing. Methods: The types, clinical manifestations and induced drugs of adverse reactions induced by compound preparations in our hospital from January 1994 to December 1998 were analyzed. Results: 75 cases of adverse reactions induced by compound preparations accounted for 26.3% of the total 285 cases of adverse reactions, 36% of moderate and severe symptoms, involving 12 organs / system types, induced 35 varieties of drugs, with previous adverse drug reactions History accounted for 21.3%. Conclusion: In clinical practice, adverse reactions monitoring and correlation study of compound preparations should be paid great attention to, and drug safety of compound preparations should be improved.