目的　测定乙型肝炎后肝硬化患者食管动力及胃动素的变化 ,并观察肝功能减退对食管动力及血浆胃动素的影响 ,以探讨肝硬化患者上消化道症状的发生机制方法　乙型肝炎后肝硬化患者 4 4例 (肝性脑病、重度食管静脉曲张、活动性出血及凝血酶原活动度小于 30 %者除外 )和健康对照者 Objective To determine the changes of esophageal motility and motilin in cirrhotic patients with hepatitis B and to observe the effects of hepatic dysfunction on motility of esophagus and plasma motilin in order to explore the mechanism of upper gastrointestinal symptoms in cirrhotic patients Methods Hepatitis B In 44 patients with post-cirrhosis (hepatic encephalopathy, severe esophageal varices, active bleeding and prothrombin activity less than 30% except) and healthy controls