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目的探讨胃镜下氩离子凝固术对幽门螺杆菌阴性疣状胃炎的治疗效果。方法对幽门螺杆菌阴性成熟型疣状胃炎62例,随机分为两组,治疗组42例,在胃镜下行氩离子凝固术,术后予埃索美拉唑(耐信)20mg,Bid,治疗4周,对照组20例,予埃索美拉唑(耐信)20mg,Bid,治疗4周,疗程后复查胃镜和行临床症状随访。结果治疗组临床症状改变和内镜病灶消失的有效率显著高于对照组(P<0.01),经氩离子凝固术治疗的疣状胃炎患者临床症状明显改善,内镜复查病灶消失,未出现出血和穿孔等并发症。结论内镜下氩离子凝固术是治疗幽门螺杆菌阴性疣状胃炎的一种疗效确切,安全性好,副作用少的方法,值得推荐。
Objective To investigate the therapeutic effect of endoscopic argon plasma coagulation on Helicobacter pylori negative verrucous gastritis. Methods 62 cases of Helicobacter pylori negative mature verrucous gastritis were randomly divided into two groups, 42 cases in the treatment group, argon plasma coagulation under gastroscope and esomeprazole 20 mg bid after treatment 4 weeks, the control group of 20 cases, to esomeprazole (resistant) 20mg, Bid, for 4 weeks after treatment, gastroscopy and clinical symptoms were followed up. Results The clinical symptoms and the disappearance of endoscopic lesions in treatment group were significantly higher than those in control group (P <0.01). The clinical symptoms of verrucous gastritis patients treated with argon plasma coagulation were significantly improved. The lesions of endoscopy were disappeared and no hemorrhage occurred And complications such as perforation. Conclusion Endoscopic argon plasma coagulation is an effective and safe method for the treatment of H. pylori-negative verrucous gastritis. It is worth recommending.