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目的探讨阿托伐他汀钙对脑梗死患者血脂、超敏C反应蛋白和动脉粥样硬化的影响。方法选取医院收治的脑梗死患者88例,随机分为研究组与对照组,每组44例。对照组给予常规治疗,研究组在对照组基础上应用阿托伐他汀钙治疗。观察2组临床效果。结果治疗后,2组血脂水平均较治疗前改善,且研究组改善程度优于对照组,差异有统计学意义(P<0.05)。治疗后2组超敏C反应蛋白、颈动脉中层内膜厚度均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.01)。研究组治疗后动脉粥样斑块治疗总有效率93.18%,高于对照组的72.72%,差异有统计学意义(P<0.01)。结论阿托伐他汀钙治疗脑梗死疗效较好。
Objective To investigate the effects of atorvastatin calcium on serum lipids, high-sensitivity C-reactive protein and atherosclerosis in patients with cerebral infarction. Methods Eighty-eight patients with cerebral infarction admitted to hospital were randomly divided into study group and control group, 44 cases in each group. Control group was given conventional treatment, the study group in the control group based on the application of atorvastatin calcium treatment. Two groups observed the clinical effect. Results After treatment, the levels of blood lipid in both groups improved compared with before treatment, and the improvement in study group was better than that in control group (P <0.05). After treatment, the two groups of hypersensitive C-reactive protein, carotid artery intima-media thickness were lower than before treatment, and the study group was lower than the control group, the difference was statistically significant (P <0.01). The total effective rate of atherosclerotic plaque treatment in study group was 93.18%, which was higher than that in control group (72.72%), the difference was statistically significant (P <0.01). Conclusions Atorvastatin calcium is effective in treating cerebral infarction.