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检测了130例反复中上腹痛患儿及95例消化道疾病的成人和50例健康儿童血清抗-HPIgG,结果显示:成人消化组抗—HPIgG阳性率显著高于儿童消化组(P<0.01),儿童消化组抗-HPIgG阳性率显著高于健康儿童组(P<0.05),儿童消化组不同年龄段间无明显差异(P>0.05),但随年龄增加有上升趋势,大年龄组抗—HPIgG阳性检出率与成人相近,说明儿童HP感染率较高,我们认为儿童血清抗—HPIgG的检测,有助于指导临床及早控制及根治儿童HP感染。对预防HP感染所致的消化性溃疡,甚至胃癌的发生具有重要意义。
The anti-HPIgG was detected in 130 cases of children with middle-upper abdominal pain and 95 cases of gastrointestinal diseases and 50 healthy children. The results showed that the positive rate of anti-HPIgG in adult digestion group was significantly higher than that in children (P <0. 01). The positive rate of anti-HlPgG in children with digestive tract was significantly higher than that in healthy children (P <0.05). There was no significant difference between children in different age groups (P> 0.05), but increased with age . The positive detection rate of anti-HPIgG in older age group is similar to that in adults, indicating that HP infection rate is high in children. We think that the detection of anti-HPIgG in children serum will help to guide clinical control and eradicate HP infection in children early. To prevent HP infection caused by peptic ulcer, and even the occurrence of gastric cancer is of great significance.