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1.序言以细胞工程和基因工程为中心的生物工程技术领域,将一个一个生物体细胞加工或加以操作的技术,仍然必不可少。以往主要使用手工操作玻璃微量吸管,此法存在需要熟练技术且缺乏再现性等问题。为此,开发使用步进马达和压电元件的机械式操纵装置(机械手),能反复进行较简单的细胞操作,但大多数仍依赖微量吸管。为使细胞操作法广泛普及和付诸实用,强烈要求从根本上革新技术。作者在10年前就从事使用激光的生物体计测、诊断和控制技术的开发研究,通过运用激光所具有的优良特性,可能实现前所未有的全
1. Introduction In the field of bioengineering, which is centered on cellular engineering and genetic engineering, the technology of processing or manipulating cells of a living organism is still indispensable. In the past mainly using hand-operated glass micropipette, this method requires the skilled and lack of reproducibility and other issues. For this reason, the development of a mechanical manipulator (manipulator) that uses a stepping motor and a piezo-electric element allows repeated simple cell operations, but most still rely on micropipettes. In order to make cell operation widely popular and put into practical use, it is strongly demanded that radically new technologies be invented. The author engaged in the research and development of laser measurement, diagnosis and control technology using laser 10 years ago. By using the excellent characteristics of laser, it is possible to realize the unprecedented