论文部分内容阅读
首先合成了单取代的β环糊精ATRP引发剂(β-CD-Br),利用核磁、质谱等对其进行了表征,并通过ATRP聚合制备了端基为β-环糊精的水溶性聚合物聚甲基丙烯酸N,N-二甲基氨基乙酯(β-CD-PDMAEMA).聚合物β-CD-PDMAEMA可以通过环糊精与金刚烷之间的主客体包结络合作用与端基为金刚烷的聚芴(PFADA)形成水溶性的聚芴纳米粒子.重点探讨了β-CD-PDMAEMA与PF-ADA的质量比和不同的组装方法对纳米粒子尺寸及分布的影响,研究表明质量比为4∶1时通过向2种聚合物的THF混合溶液中缓慢加水的方法可得到流体力学半径(R_h)为80 nm、PDI为0.11的纳米粒子.最后利用透射电子显微镜和原子力显微镜对纳米粒子的形貌进行了表征,进一步依照纳米粒子的R_h随温度升高的实验可以证实纳米粒子具有明显的核壳结构,其中刚性的聚芴为核半径约为50 nm,水溶性的PDMAEMA聚合物为壳.
The monosubstituted β-cyclodextrin ATRP initiator (β-CD-Br) was synthesized and characterized by NMR and MS. ATRP-terminated water-soluble polymer was prepared by ATRP polymerization Poly (β-CD-PDMAEMA) Polymers of β-CD-PDMAEMA can be complexed by host-guest binding between cyclodextrin and adamantane Water-soluble polyfluorene nanoparticles were formed by polyfluorene (PFADA) based on adamantane. The effects of the mass ratio of β-CD-PDMAEMA and PF-ADA and the different assembly methods on the size and distribution of nanoparticles were investigated. When the mass ratio is 4:1, nano-particles with hydrodynamic radius (R_h) of 80 nm and PDI of 0.11 can be obtained by slowly adding water to the mixed solution of THF and THF in the two polymers.Finally, using transmission electron microscopy and atomic force microscopy The morphologies of the nanoparticles were characterized. Furthermore, in accordance with the experiment of R_h of nanoparticles with increasing temperature, the core-shell structure of the nanoparticles was confirmed. The rigid polyfluorene was a core-shell with a radius of about 50 nm and a water-soluble PDMAEMA Things for the shell.