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摘要目的利用扩散张量成像(DTI)参数测定随年龄增长的脑白质微结构的纵向变化率,并探讨心血管危险因素是否影响这种纵向变化。材料与方法此项基于人群的前瞻性队列研究经政府监管的伦理委员会支持,以及获得所有参与者的书面知情同意书后开展,所有的参与者均居住在社区且
Abstract Objective To measure longitudinal changes of white matter microstructure with age by diffusion tensor imaging (DTI) parameters and to investigate whether cardiovascular risk factors affect this longitudinal change. Materials and Methods This population-based prospective cohort study was supported by a government-regulated ethics committee and written informed consent was obtained from all participants with all participants residing in the community