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目的:调查本地区孕早期妇女CMV感染率,了解母婴传播发生情况,及早预防,实现优生。方法:采用抗体捕获法酶联免疫吸附试验检测孕早期血清巨细胞病毒特异性抗lgM。结果:孕早期妇女感染为0.512%。其中6例自愿终止,术后将绒毛组织或胎盘送病理检查,4例发现不同程度有感染、绒毛水肿、纤维化及坏死、蜕膜血管单核细胞浸润等损害。结论:妊娠巨细胞病毒感染对胎儿危害严重,有必要对早孕妇女进行常规的筛查,有利于母婴健康。
Objective: To investigate the prevalence of CMV in pregnant women in the first trimester of the region, understand the occurrence of mother-to-infant transmission, prevent as soon as possible and achieve eugenics. Methods: Serum cytomegalovirus specific anti-lgM was detected in early pregnancy by antibody capture enzyme-linked immunosorbent assay. Results: In the first trimester, the infection was 0.512%. Among them, 6 cases were terminated voluntarily, and villi tissues or placenta were sent to pathological examination after operation. Four cases were found to have infection, villus edema, fibrosis and necrosis, and decidual vascular mononuclear cell infiltration. Conclusion: Pregnancy cytomegalovirus infection is seriously harmful to the fetus. It is necessary to conduct routine screening of pregnant women in early pregnancy, which is good for maternal and infant health.