研究了希夫碱金属［Ｃｏ（Ⅱ）、Ｍｎ（Ⅱ）、Ｚｎ（Ⅱ）、Ｈｇ（Ⅱ）］配合物为载体的阴离子选择性电极，结果表明，水杨醛二缩邻苯二胺汞（Ⅱ）对碘离子具有高的选择性，且电极呈现反Ｈｏｆｍｅｉｓｔｅｒ行为，其选择性次序为：Ｉ－＞ＳＣＮ－＞Ｂｒ－＞ＣｌＯ－４＞Ｃｌ－＞ＮＯ－２＞ＮＯ－３＞ＳＯ２－４。该电极响应速度快，具有良好的稳定性，使用寿命在三个月以上。用交流阻抗，紫外可见光谱技术研究了电极的响应机理并将电极用于药品分析，结果令人满意 The anion selective electrode of Schiff base metal [Co (Ⅱ), Mn (Ⅱ), Zn (Ⅱ) and Hg (Ⅱ)] complexes was investigated. The results showed that the salicylaldehyde- (Ⅱ) has high selectivity to iodide ions, and the electrode exhibits anti-Hofmeister behavior with the order of selectivity: I-> SCN-> Br-> ClO-4> Cl-> NO-2> NO- 3> SO2 -4. The electrode response speed, with good stability, the service life of more than three months. The electrochemical impedance spectroscopy and UV-vis spectroscopy were used to study the response mechanism of the electrodes and the electrodes were used in drug analysis with satisfactory results