目的:评价硫糖铝与黄连素在慢性顽固性胃炎治疗中的临床效果。方法:随机抽取我院收治的慢性顽固性胃炎患者60例,分为两组,分析两组治疗疗效。结果:研究组治疗后临床总有效率90.00%,高于对照组临床总有效率76.67%(P<0.05);研究组疾病复发率6.67%;低于对照组的复发率23.33%(P<0.05)。结论:硫糖铝与黄连素联合治疗慢性顽固性胃炎的临床效果显著,值得推广。 Objective: To evaluate the clinical effect of sucralfate and berberine in the treatment of chronic intractable gastritis. Methods: A total of 60 patients with chronic refractory gastritis admitted in our hospital were randomly divided into two groups. The curative effects of the two groups were analyzed. Results: The total effective rate of the study group after treatment was 90.00%, which was significantly higher than that of the control group (76.67%, P <0.05). The recurrence rate was 6.67% in the study group and 23.33% (P <0.05) ). Conclusion: The clinical effect of sucralfate and berberine in the treatment of chronic refractory gastritis is significant and worthy of promotion.