B细胞在免疫系统中可以发挥多种功能,主要是通过递呈抗原和产生抗体起到免疫调节作用。B细胞与其他淋巴细胞相似,既可以诱发疾病,也可以阻止疾病的发展、减轻疾病的严重性[1]。如在自身免疫性疾病中,B细胞释放自身抗体损伤靶组织,因此,被认为是致病因素;但是,其所释放的自身抗体 B cells in the immune system can play a variety of functions, mainly through the presentation of antigens and antibodies play an immunomodulatory role. B cells and other lymphocytes similar to both disease can also prevent the development of the disease and reduce the severity of the disease [1]. As in autoimmune diseases, B cells release autoantibodies to damage the target tissues and, therefore, are thought to be causative agents; however, autoantibodies released by them