原发性高血压不仅是血流动力学异常疾病,而且也伴随脂肪、糖代谢紊乱和心、脑、肾等靶器官的不良重塑。因此治疗要在有效控制血压水平的同时,改善上述诸代谢紊乱,预防和逆转靶器官的不良重塑,这是降低心血管并发症的发生和病死率的关键[1]。1抗高血压药物评价1.1利尿剂大规模临 Essential hypertension is not only an abnormal hemodynamic disease, but also accompanied by fat, glucose metabolism disorder and heart, brain, kidney and other target organs of poor remodeling. Therefore, the treatment should be effective in controlling blood pressure levels, while improving the above metabolic disorders, prevention and reversal of target remodeling of poor, which is to reduce the incidence of cardiovascular complications and mortality is the key [1]. 1 antihypertensive drug evaluation 1.1 diuretic large-scale Pro