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目的:比较2种方案治疗口服降糖药无效的2型糖尿病的药物经济学效果。方法:采用回顾性调查,利用药物经济学方法对艾塞那肽注射液联合二甲双胍缓释片(A组),甘精胰岛素注射液联合二甲双胍缓释片(B组)治疗口服降糖药无效的2型糖尿病的方案进行分析。结果:A组和B组的总有效率分别为86.96%和83.72%,差异无统计学意义(P>0.05)。A组和B组的药物成本分别为3 032.7元,623.4元,B组的药物成本低于A组。结论:2种治疗方案均能将血糖控制在相对理想的范围内,但B方案治疗2型糖尿病的经济效果较优。
OBJECTIVE: To compare the pharmacoeconomic efficacy of two regimens in the treatment of type 2 diabetes in which oral hypoglycemic agents are ineffective. Methods: A retrospective survey was conducted to evaluate the efficacy of exenatide injection in combination with metformin extended-release tablets (group A) and insulin glargine injection plus metformin extended-release tablets (group B) in the treatment of oral hypoglycemic agents Type 2 diabetes program for analysis. Results: The total effective rates in group A and group B were 86.96% and 83.72% respectively, with no significant difference (P> 0.05). The costs of drugs in group A and group B were 3 032.7 yuan and 623.4 yuan respectively, while those in group B were lower than those in group A. Conclusion: Both of the two treatment regimens can control blood glucose within a relatively ideal range, but the economic benefit of type B diabetes mellitus is better than that of type B diabetes mellitus.