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目的:为沙棘油的进一步开发和利用提供理论根据。方法:低温下大鼠口服沙棘油或维生素E后,用放免法测定血及肝组织中环核苷酸含量的变化。结果:单纯低温组环核苷酸含量持续增高;低温同时给沙棘油或维生素E组环核苷酸含量与常温对照组比较,增高不明显,尤以沙棘油更接近对照组水平。结论:沙棘油也可通过对低温下大鼠体内环核苷酸代谢的影响,促进机体对寒冷的适应,其作用优于同等剂量的维生素E。
Objective: To provide theoretical basis for the further development and utilization of seabuckthorn oil. Methods: After oral administration of seabuckthorn oil or vitamin E to rats at low temperature, the contents of cyclic nucleotides in blood and liver tissues were determined by radioimmunoassay. Results: The content of nucleotides in the hypothermia group continued to increase. At the same time, the content of cyclic nucleotides in the seabuckthorn oil or vitamin E group was not significantly increased compared with the normal temperature control group, especially the seabuckthorn oil was closer to the control group. Conclusion: Seabuckthorn oil can also promote the body’s adaptation to the cold by its effect on the nucleotide metabolism of the nucleus in rats at low temperature, which is better than the same dose of vitamin E.