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目的分析浙江省湖州市全球基金结核病流动人口项目实施前后流动人口结核病防治效果,为进一步加强流动人口结核病防治工作提供依据。方法收集湖州市2005年1月至2012年6月登记的流动人口结核病患者资料,以全球基金项目实施后(2008年10月到2012年6月)登记的流动人口结核病患者为研究组,以项目实施前(2005年1月至2008年9月)登记的流动人口结核病患者为对照组,对比分析项目实施前与实施后的患者治疗转归情况。结果研究组共登记流动人口结核病患者1596例;对照组共登记流动人口结核病患者1084例。新涂阳肺结核患者治愈率由项目前的81.0%上升到89.2%(χ2=13.17,P<0.01);复治涂阳患者治愈率虽然由65.9%上升为76.4%(χ2=1.28,P=0.26),但差异无统计学意义;涂阴患者完成疗程率由73.7%上升为90.0%(χ2=37.88,P<0.01)。年龄组中,44岁以下新涂阳患者的研究组及对照组治愈率差异有统计学意义(χ2=13.34,P<0.01);涂阴患者在不同年龄组的研究组及对照组治疗完成率差异均有统计学意义。不同职业分类,新涂阳肺结核患者中,民工的研究组与对照组治愈率差异有统计学意义(χ2=13.64,P<0.01);涂阴患者,除服务业,其他职业研究组与对照组治愈率差异均有统计学意义。结论通过项目实施,流动人口的结核病患者治疗转归情况具有很大改善,有针对性地进行干预,可有效提高结核病控制效果。
Objective To analyze the effect of prevention and control of tuberculosis among floating population before and after the implementation of TBF program in Huzhou City, Zhejiang Province, and to provide basis for further strengthening TB prevention and control work among floating population. Methods The data of TB patients registered in Huzhou City from January 2005 to June 2012 were collected. The TB patients registered as migrant population after the implementation of the Global Fund Project (October 2008 to June 2012) Before implementation (January 2005 to September 2008), registered TB patients were control group, and the outcomes of patients’ treatment before and after implementation were compared. Results The study group registered a total of 1596 cases of floating population of tuberculosis patients; control group registered a total of 1084 cases of floating population tuberculosis patients. The cure rate of new smear-positive pulmonary tuberculosis patients increased from 81.0% before the project to 89.2% (χ2 = 13.17, P <0.01). Although the cure rate of smear-positive patients increased from 65.9% to 76.4% (χ2 = 1.28, P = ), But the difference was not statistically significant. The rate of completion of treatment of patients with smear-negative was increased from 73.7% to 90.0% (χ2 = 37.88, P <0.01). In the age group, the cure rates of the study group and the control group under the age of 44 were statistically different (χ2 = 13.34, P <0.01); the cure rate of the study group and the control group The differences were statistically significant. In different occupational categories, the new smear positive tuberculosis patients, migrant workers in the study group and the control group, the cure rate was significantly different (χ2 = 13.64, P <0.01); smear negative patients, except for service, other occupational groups and control groups Differences in cure rates were statistically significant. Conclusion Through the implementation of the project, the treatment outcomes of TB patients among floating population have greatly improved. Intervention can effectively improve the control effect of tuberculosis.