反射式共聚焦显微镜是继皮肤镜、皮肤超声等仪器后新出现应用于皮肤科的辅助诊断技术。该项技术在皮肤恶性黑素瘤诊断中的应用是目前研究热点。在体、无创、高分辨率的特点使其适用于皮肤恶性黑素瘤的诊断、辅助治疗及随访中。该文对反射式共聚焦显微镜在皮肤恶性黑素瘤的应用进行综述。 Reflective confocal microscope is the second after dermatology, skin ultrasound and other equipment emerging in dermatology diagnostic techniques. The application of this technique in the diagnosis of skin malignant melanoma is currently a hot research topic. In vivo, non-invasive, high-resolution features make it suitable for the diagnosis, adjuvant treatment and follow-up of cutaneous malignant melanoma. This article reviews the application of reflection confocal microscopy in the diagnosis of cutaneous malignant melanoma.