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目的了解丙型肝炎(丙肝)哨点5类监测人群(肾透析人群、无偿献血人群、医院侵入性诊疗人群、单位体检检群、计划生育门诊就诊人群)丙肝病毒(HCV)感染状况及趋势,为丙肝综合防治和科学干预提供信息和依据。方法 2010-2012年,在每年4-6月,使用连续性监测方法收集5类监测人群的血样,完成HCV抗体的实验室检测,并进行描述和分析。结果 2010-2012年,5类监测人群中,肾透析人群哨点HCV抗体阳性率(均数)均超过5%(0~25.3%);医院侵入性诊疗人群HCV阳性率为0.7%~0.9%;除2010年无偿献血人群HCV抗体阳性率为0.6%外,其他年份单位体检人群、无偿献血人群、计划生育门诊就诊人群的HCV抗体阳性率均低于0.5%。结论肾透析人群的感染率持续处于较高水平,而其他丙肝哨点监测人群HCV抗体阳性率较低。血液传播是目前中国HCV传播的主要途径,如何避免或降低HCV传播的风险,是当前和今后应当重视和亟待解决的问题。
Objective To investigate the status and trends of hepatitis C virus (HCV) infection in five monitoring groups of hepatitis C (hepatitis C) sentinel patients (renal dialysis population, non-remunerated blood donation group, hospitals invaded clinics, unit body examination group and family planning outpatient clinic population) For the comprehensive prevention and treatment of hepatitis C and scientific interventions to provide information and basis. Methods From April to June of each year, blood samples of five types of monitoring population were collected by continuous monitoring method from 2010 to 2012. The laboratory tests of HCV antibodies were completed and described and analyzed. Results The positive rates (mean) of sentinel HCV antibody in 5 dialysis outpatients were more than 5% (0 ~ 25.3%) in the 5 types of monitoring population from 2010 to 2012. The positive rate of HCV in invasive treatment group was 0.7% -0.9% . In addition to the positive rate of HCV antibody in unpaid blood donors was 0.6% in 2010, the positive rates of HCV antibodies in unit health checkups, unpaid blood donors and family planning outpatients in other years were lower than 0.5%. Conclusion The infection rate of renal dialysis patients remains at a high level, while the HCV antibody positive rate in other HCV sentinel surveillance sites is low. Blood transmission is the main way of HCV transmission in China at present. How to avoid or reduce the risk of HCV transmission is a problem that should be paid attention to and urgently needs to be solved now and in the future.