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结合内镜检查,从粘液池抽取清晨空腹胃液进行 pH、游离酸、蛋白酶、粘液、胆汁酸及 DNA 的同步测定,运用微机处理数据。结果证示:pH值以十二指肠消化性溃疡组最低;胃癌组最高;浅表、浅表萎缩及萎缩性胃炎依次递升,后者稍低于胃癌组;胆汁返流组居第三位。游离酸含量的分布情况与 pH 恰好对应相反。蛋白酶含量的分布情况与游离酸相仿,但在浅表性胃炎组即有明显的减少。所有胃病组的粘液含量均明显低于正常,而以胆汁返流组最低,其次是胃癌,萎缩性胃炎组的粘液含量与胃溃疡组相似。胃液胆汁酸以胆汁返流组最高,其次为胃癌,三种胃炎与二种溃疡病组间未见明显差异,但均显著高于正常。DNA 含量以胃癌组最突出,其次是胆汁返流组,其余情况与胆汁酸的分布特点相同。上述研究为临床进行胃功能检查及鉴别诊断提供了有价值的资料。
In combination with endoscopy, a fasting gastric juice was collected from the mucus pool for the simultaneous determination of pH, free acid, protease, mucus, bile acid, and DNA, and the data was processed using a computer. The results showed that the pH value was the lowest in the duodenal peptic ulcer group; the gastric cancer group was the highest; superficial, superficial atrophy, and atrophic gastritis were progressively increased; the latter was slightly lower than that of the gastric cancer group; the bile reflux group ranked third . The distribution of free acid content corresponds exactly to the pH. The distribution of protease content is similar to that of free acid, but it is significantly reduced in the superficial gastritis group. The gastric mucus content in all gastric disease groups was significantly lower than normal, while the bile reflux group was the lowest, followed by gastric cancer. The mucus content in the atrophic gastritis group was similar to that in the gastric ulcer group. Gastric bile acid was the highest in the bile reflux group, followed by gastric cancer. There was no significant difference between the three gastritis and the two types of ulcer disease groups, but all were significantly higher than normal. The DNA content was most prominent in the gastric cancer group, followed by the bile reflux group. The remaining conditions were the same as those of bile acids. The above studies provide valuable information for clinical gastric function tests and differential diagnosis.