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目的评价急性ST段抬高心肌梗死(STEMI)患者血糖水平增高与急诊介入治疗(PCI)前患者冠状动脉TIMI血流的相关性。方法选择120例STEMI行急诊PCI治疗的患者,收集患者入院前全血血糖、PCI前冠状动脉造影梗死相关血管TIMI血流以及患者临床资料。血糖≥7·8mmol/L(140mg/dL)定义为高血糖症。结果在接受急诊PCI术前仅有18例(15%)患者冠状动脉造影血流达到TIMI3级,高血糖症患者87例(72·5%)。正常血糖组在PCI术前TIMI3级的患者多于高血糖症组(两组分别为27·3%和10·3%,P<0·01),但两组随诊期间主要心脏事件的发生率差异无统计学意义。结论高血糖症是STEMI患者PCI前冠状动脉TIMI血流重要的预测因素之一。
Objective To evaluate the correlation between elevated blood glucose levels in patients with acute ST-segment elevation myocardial infarction (STEMI) and TIMI flow in patients with coronary artery prior to emergency intervention (PCI). Methods A total of 120 STEMI patients undergoing PCI were enrolled in this study. Pre-admission blood glucose, TIMI flow related to coronary angiography before PCI, and clinical data were collected. Blood glucose ≥7 · 8mmol / L (140mg / dL) is defined as hyperglycemia. Results Only 18 (15%) patients underwent coronary angiography before TIMI3 and 87 (72.5%) patients with hyperglycemia. The patients with TIMI3 grade in the normal blood glucose group had more TIMI3 grade than the hyperglycemia group (27.3% and 10.3% in both groups, P <0.01), but the incidence of major cardiac events during follow-up in both groups No significant difference in rates. Conclusion Hyperglycemia is one of the most important predictors of TIMI flow in pre-PCI coronary artery in patients with STEMI.