新型重组人ＴＮＦ对小鼠和大鼠的毒性观察张淑英，袁伯俊，陆国才，刘俊平，张璞肿瘤坏死因子（ＴＮＦ）以具有巨大应用潜力的抗肿瘤特性而受到普遍重视。但从已发表的实验结果来看，其效果并不象动物实验结果那样显著，且毒副作用大，全身用药时可引起高热、低血压、震颤... Toxicity of New Recombinant Human TNF in Mice and Rats ZHANG Shu-ying, YUAN Bo-jun, LU Guo-cai, LIU Jun-ping, ZHANG Pu Tumor necrosis factor (TNF) is widely regarded as an antitumor agent with great potential for application. However, the published experimental results show that the effect is not as significant as the animal experimental results, and toxic side effects, systemic medication can cause fever, hypotension, tremor ...