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目的:探讨多囊卵巢综合征(PCOS)糖耐量异常的发生率及体重指数和腰身比值预测PCOS患者糖耐量异常的可靠性。方法:选择2004年1月～2007年12月期间青岛大学医学院附属烟台毓璜顶医院接诊的192例14～39岁的PCOS患者(其中14～19岁的青春期PCOS患者57例、20～39岁的成年女性病例135例),测定体重指数和腰身比值;测定空腹血糖水平并行口服糖耐量试验。结果:21.4%的PCOS患者糖耐量异常,其中12.3%的青春期患者和25.2%的成年患者糖耐量异常。分别比较青春期和成年PCOS患者糖耐量异常与糖耐量正常者之间体重指数和腰身比值的差异,两组体重指数之间不存在显著性差异(P>0.05),而腰身比值存在显著性差异(P<0.05)。结论:单纯体重指数不能用于预测PCOS患者糖耐量异常的发生,而腰身比值可作为预测PCOS患者糖耐量异常发生的简易指标。
Objective: To investigate the incidence of PCOS impaired glucose tolerance and body mass index and waist-to-waist ratio in predicting the reliability of impaired glucose tolerance in patients with PCOS. METHODS: A total of 192 PCOS patients (aged from 14 to 39 years) with adolescent PCOS who were admitted to Yantai Yuhuangding Hospital Affiliated to Qingdao University Medical College from January 2004 to December 2007 were selected (57 adolescent PCOS patients aged from 14 to 19, 20 to 39 years old Of 135 cases of adult women), determination of body mass index and waist-to-body ratio; determination of fasting blood glucose levels in parallel with oral glucose tolerance test. RESULTS: 21.4% of PCOS patients had impaired glucose tolerance, 12.3% of adolescents and 25.2% of adults had impaired glucose tolerance. Body mass index and waist-to-waist ratio were compared between impaired glucose tolerance and normal glucose tolerance in adolescent and adult patients with PCOS. There was no significant difference between the two groups in body mass index (P> 0.05), but the waist-to-waist ratio was significantly different P <0.05). Conclusion: BMI alone can not be used to predict the occurrence of impaired glucose tolerance in patients with PCOS. The waist-to-waist ratio can be used as a simple predictor of impaired glucose tolerance in patients with PCOS.