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目的探讨进展型脑梗死的危险因素。方法 96例进展型脑梗死作为观察组,110例非进展型脑梗死患者作为对照组。测定两组患者的血压、血脂、血糖、血尿酸、超敏C反应蛋白(hs-CRP)、D-二聚体和同型半胱氨酸(Hcy)。结果两组在年龄、性别、吸烟史方面无显著性差异(P>0.05)。两组患者在胆固醇(TC),甘油三脂(TG),收缩压(SBP)方面无明显差异,在血糖(FPG),低密度脂蛋白(LDL-C),高密度脂蛋白(HDL),舒张压(DBP)方面有显著性差异(P<0.05)。观察组在尿酸、hs-CRP、D-二聚体和Hcy方面与对照组有明显差异(P<0.05,P<0.01)。结论舒张压、低密度脂蛋白、尿酸、hs-CRP、D-二聚体和Hcy是脑梗死进展的危险因素。
Objective To explore the risk factors of progressive cerebral infarction. Methods 96 cases of progressive cerebral infarction as observation group and 110 cases of non-progressing cerebral infarction as control group. Blood pressure, blood lipid, blood glucose, serum uric acid, hs-CRP, D-dimer and homocysteine (Hcy) were measured in two groups. Results There were no significant differences in age, sex and smoking history between the two groups (P> 0.05). There were no significant differences in TC, TG and SBP between the two groups, but there was no significant difference between the two groups in blood glucose, LDL-C, HDL, There was a significant difference in DBP (P <0.05). There was significant difference between the observation group and the control group in uric acid, hs-CRP, D-dimer and Hcy (P <0.05, P <0.01). Conclusion Diastolic blood pressure, low density lipoprotein, uric acid, hs-CRP, D-dimer and Hcy are the risk factors for the progression of cerebral infarction.