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患者女,18岁,学生。因发热、全身乏力半月余入院。起病前2周有服用解热镇痛药及磺胺药史。服药前1周曾查外周 WBC11×10~9/L,其中 N86%,L14%,其余两系正常。入院时 T39.6℃,P120次/分,贫血貌,皮肤少许淤点,躯干可见药疹数枚。实验室检查:RBC2.2×10~(12)/L,WBCl.3×10~9/L,N29%,L61%,单核细胞3%,血小板60×10~9/L,网织红细胞0.1%。骨髓象示有核细胞增生重度降低,粒系中杆状核细胞30%,成熟粒细胞3.0%,余阶段均未见。成熟单核细胞8.0%,成熟淋巴细胞79%,浆细胞1.0%,红系未见。巨核系中过度巨1个,余未见。符合急性再生障碍性贫血。
Patient female, 18 years old, student. Due to fever, malaise more than half a month admitted to hospital. 2 weeks before onset, taking antipyretic analgesics and sulfa drug history. One week before taking the drug, we examined the peripheral WBC11 × 10 ~ 9 / L, of which N86%, L14%, the other two normal. Admission T39.6 ℃, P120 beats / min, anemia appearance, a little skin bruising, the body can be seen a few drug eruption. Laboratory tests: RBC2.2 × 10-12 / L, WBCl.3 × 10-9 / L, N29%, L61%, monocytes 3%, platelets 60 × 10-9 / L, reticulocytes 0.1%. Bone marrow showed a severe reduction of nuclear proliferation, 30% of the granulocytes in the rod, 3.0% of mature granulocytes, the remaining stage were not seen. Mature mononuclear cells 8.0%, mature lymphocytes 79%, plasma cells 1.0%, no red line. Mega nuclear giant over 1, I have not seen. In line with acute aplastic anemia.