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目的：研究真菌与慢性胃粘膜病变的关系。方法：采用真菌培养、生化试验及组织病理学检查方法，对１２９例患各种慢性胃病患者进行了胃液、胃病变部活检组织的检查。其中慢性浅表性胃炎２６例，慢性萎缩性胃炎２２例，胃溃疡４８例，胃癌３３例。正常对照８例。结果：胃液、胃活检组织在各类胃部疾患的真菌检出率分别为：慢性浅表性胃炎为６１．５％和６９．２３％；慢性萎缩性胃炎均为６３．６４％；胃溃疡为７７．０８％和６８．７５％；胃癌为７５．７６％和８４．８４％。正常对照为５０％。经卡方检验，各胃部疾患组与正常对照组相比无统计学差异（ ｐ＞ ０． ０５）。慢性胃粘膜病变所分离真菌为：念珠菌属、酵母菌、青霉、曲霉、链格孢和毛霉菌。结论：慢性胃粘膜病变所分离出的优势菌为白念和类星形念珠菌，次优势菌为曲霉菌和青霉菌。研究结果不能显示胃粘膜疾患与真菌之间的关系。
Objective: To study the relationship between fungi and chronic gastric mucosal lesions. Methods: Fungal culture, biochemical tests and histopathological examination were used to examine the biopsy tissues of gastric and gastric lesions in 129 patients with various chronic gastritis. Of which 26 cases of chronic superficial gastritis, chronic atrophic gastritis in 22 cases, gastric ulcer in 48 cases, 33 cases of gastric cancer. Normal control in 8 cases. Results: The prevalences of fungi in gastric diseases and stomach biopsy were 61.5% and 69.23% for chronic superficial gastritis and 63.64% for chronic atrophic gastritis respectively. Gastric ulcer 77.08% and 68.75% respectively; gastric cancer was 75.76% and 84.84%. Normal control is 50%. The chi-square test, the stomach disorders group compared with the normal control group was no significant difference (p> 0.05). Chronic gastric mucosal lesions isolated fungi: Candida, yeast, Penicillium, Aspergillus, Alternaria and Mucor. Conclusion: The predominant bacteria isolated from chronic gastric mucosal lesions are Candida albicans and Candida glabra, and the second dominant bacteria are Aspergillus and Penicillium. The results do not show the relationship between gastric mucosal disorders and fungi.