粘膜皮肤淋巴结综合征(mucocutaneouslymph node syndrome,简称MLNS)是川崎在1942年首次报告的一种原因不明的发热出疹性疾病。其主要临床特点是持续性发热、粘膜皮肤弥漫性泛红、两眼结膜充血、颈淋巴结肿大和手足硬肿,偶有关节痛等。他经过多年仔细观察,于1967年报告50例,并定名为急性发热性粘膜皮肤淋巴结综合征(acute febrile mucocutaneous lymph nodesyndrome)。此综合征是儿科中一种新的、自限性的、独特的重要疾病。本病最初在日本 Mucocutaneouslymph node syndrome (MLNS) is an unknown cause of fever and rash disease reported by Kawasaki for the first time in 1942. The main clinical features are persistent fever, diffuse mucocutaneous redness of the skin, conjunctival congestion of both eyes, cervical lymph nodes and hand, foot and neck sclerosis, occasional joint pain and so on. After years of careful observation, he reported 50 cases in 1967 and named it acute febrile mucocutaneous lymph node syndrome. This syndrome is a new pediatric, self-limiting, unique and important disease. The disease was originally in Japan