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目的 :探讨尖锐湿疣的临床病理特征 ,对其诊断和鉴别诊断进行讨论。方法 :收集我科 10 0例尖锐湿疣患者活检标本 ,用 10 %福尔马林固定 ,HE染色 ,并以石蜡切片组织常规 ABC法免疫组化染色检测人乳头状瘤病毒衣壳抗原 (HPV-Ag)。结果 :尖锐湿疣发病高峰年龄 2 0～ 30岁 ,好发部位肛门、生殖器 ,尖锐湿疣组织的特征性改变是光镜子下见到的挖空细胞 ;免疫组化显示尖锐湿疣 HPV- Ag阳性率达 70 .0 %。结论 :尖锐湿疣为常见性传播疾病的一种 ,掌握其临床病理特征 ,有利于明确诊断
Objective: To investigate the clinical and pathological features of condyloma acuminatum and discuss its diagnosis and differential diagnosis. Methods: A total of 100 cases of condyloma acuminatum were collected from 10 patients with condyloma acuminatum. The specimens were fixed in 10% formalin and stained with hematoxylin and eosin (HE). The normal human papillomavirus (ABC) Ag). Results: The peak age of condyloma acuminatum was 20 ~ 30 years old. The characteristic changes of the anus, genitalia and condyloma acuminatum were the hollowed-out cells seen under light microscope. The positive rate of HPV-Ag in condyloma acuminatum 70 .0%. Conclusion: Condyloma acuminatum is one of the most common sexually transmitted diseases and its clinical and pathological features are helpful to confirm the diagnosis