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本作者采用对照方法,将血浆脂蛋白(a)(Lp(a))作为PTCA后再狭窄的测定因子,并研究其预测价值。方法:69例患者均在做PTCA后1周~10个月内重新入院(85%因心绞痛。不包括心脏急症和急性心肌梗塞的病人),根据年龄、性别、糖尿病、心绞痛病史及血管造影(PTCA半径减少百分数)等因素测定。在20例无(半径减少<50%;A组)再狭窄,40例有(半径减少≥50%;B组)再狭窄的两组中,对胆固醇总量、甘油三脂、高和低密度脂蛋白、apoA-Ⅰ、apoB测定结果,两组无明显差别,而Lp(a)的测定出现显著性差别。
In this study, we used a controlled trial of plasma lipoprotein (a) (Lp (a)) as a measure of restenosis after PTCA and investigated its predictive value. Methods: All 69 patients were re-admitted within 1 week to 10 months after PTCA (85% of patients with angina pectoris, excluding cardiac emergencies and acute myocardial infarction), according to age, gender, diabetes mellitus, history of angina and angiography PTCA radius reduction percentage) and other factors. Total cholesterol, triglycerides, high and low densities were measured in 20 patients with no (50% reduction in radius; group A) restenosis and 40 patients with restenosis (radius reduction ≥50%; group B) Lipoprotein, apoA-Ⅰ, apoB determination results, no significant difference between the two groups, while the determination of Lp (a) showed significant differences.