论文部分内容阅读
目的:了解我院药品不良反应(ADR)发生情况及引发ADR的相关因素,促进临床合理用药。方法:把我院2007年收集到的117例ADR进行分类汇总,并加以分析。结果:117例ADR中男孩居多76例,女孩41例,化学药品引发104例,中成药引发13例。在117例ADR中,静脉给药者居多,占总例数的88.9%(104例),抗微生物药引起的ADR居首位,共32种药物引起56例ADR。皮肤及其附件损害是ADR最主要的表现,占总例数的68.4%(80例)。结论:儿童ADR的发生男孩比女孩多,ADR的发生与给药途径、药品种类等多种因素相关,应加强ADR的监测及相关知识的宣传,以减少和避免ADR的发生。
Objective: To understand the incidence of adverse drug reaction (ADR) in our hospital and the related factors that lead to ADR, to promote clinical rational use of drugs. Methods: A total of 117 cases of ADR collected in our hospital in 2007 were collected and analyzed. Results: Among the 117 ADRs, 76 were boys, 41 were girls, 104 were caused by chemicals and 13 were caused by proprietary Chinese medicines. Among 117 ADRs, intravenous drug users were the majority, accounting for 88.9% (104 cases) of the total number of cases. Anti-microbial drugs caused the highest ADR. A total of 32 drugs caused 56 ADRs. Damage to the skin and its appendages is the most important manifestation of ADR, accounting for 68.4% (80 cases) of the total number of cases. Conclusion: There are more boys than girls in ADR. The incidence of ADR is related to the route of administration, the type of drugs and other factors. The monitoring of ADR and the promotion of relevant knowledge should be strengthened to reduce and avoid the occurrence of ADR.