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性早熟是临床常见的儿童内分泌疾病,发病机制目前仍不清楚,营养结构、遗传、地域及环境因素被认为与性早熟发病关系密切。环境内分泌干扰物具有独特的直接或间接作用于机体的生物特性,对儿童正常的生长发育产生促进作用或延迟作用,表现为性发育提前或延迟,为性早熟发病的重要病因之一,了解及研究其与儿童性早熟的相关性,可为实施早期干预、预防性早熟的发生发展、降低中枢性性早熟发生率提供科学依据。
Precocious puberty is a common clinical endocrine disease in children, the pathogenesis is still not clear, nutrition structure, genetic, geographical and environmental factors are considered to be closely related to the pathogenesis of precocious puberty. Environmental endocrine disruptors have a unique biological role directly or indirectly on the body, the normal growth and development of children have a role in promoting or delaying the performance of sexual development in advance or delay, as one of the important causes of precocious puberty, and understand and Studying its correlation with precocious puberty may provide a scientific basis for implementing early intervention, preventing the occurrence and development of precocious puberty and reducing the incidence of central precocious puberty.