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三维适形放疗 ( 3DCRT)能够提高治疗比 ,使非小细胞肺癌 (NSCLC)局部控制率的提高成为可能。在三维适形放疗中靶区的确定是重要的一步。目前临床医师在CT图像上逐层勾画肿瘤体积 (GTV) ,根据对肿瘤生物学的了解及临床经验在GTV外周加一定边界以包括亚临床浸润病灶构成临床靶体积 (CTV) ,并根据肿瘤部位及患者具体情况 ,综合考虑呼吸动度、摆位误差等不确定因素在CTV外加 0 .5cm～ 2cm的边界构成计划靶体积 (PTV)。CTV、PTV的范围尚无统一标准。现综述靶区确定方面的研究动态
Three-dimensional conformal radiotherapy (3DCRT) can improve the treatment ratio, so that non-small cell lung cancer (NSCLC) to increase the local control rate possible. Target determination in 3D conformal radiotherapy is an important step. At present, clinicians outline the tumor volume (GTV) on the CT images layer by layer. Based on the understanding of tumor biology and clinical experience, add certain boundaries on the periphery of GTV to include subclinical infiltration lesions to form clinical target volume (CTV) And the patient’s specific situation, taking into account the uncertainties such as respiratory rate and setting error, the planned target volume (PTV) is formed on the boundary of CTV plus 0 .5 cm to 2 cm. There is no uniform standard for the range of CTV and PTV. Now review the target area to determine the research developments